Multiple hazard rooms
There will be rooms in your house that just have too many things to consider. Places with multiple entrances are a definite no-no. Specific rooms such as kitchens, bathrooms and laundry rooms can also be hazardous. Bathrooms may have a drowning threat while laundry rooms leave the possibility for pets to go into the exposed bottom of the dryer where there is a lot of wiring.
Some furniture can also pose a risk. Consider recliners for example. If your pet gets under one he could get severely hurt by the inner workings. Rocking chairs could also pose an obvious problem of severe injury.
The best policy
The best possible option is having a room that is completely empty, but not many people have that kind of empty space. The best thing to do is supervise your pet’s playtime and make sure he isn’t doing anything irresponsible. During this time, be sure to lock yourself in whatever room you choose so someone can’t inadvertently open the door. Small pets are very good at darting out of doors when given the opportunity.
If you are proactive in keeping your pet safe while he is loose yet confined, you will likely not experience any problems.